sodium starch glycolate(CMS)

CMS--Sodium Carboxymethyl Starch used in paper-making industry as retaining moisture and fluidizing.

 

 

Acting as super ordinary tablet disintegrant, CMS's effect is starch and CMC's tens of times. It's grain roll gender is good, and it's able to be pummeled into pieces directly. CMS also can be as the plasma volume extenders,and as the amplifier in cream preparation.

 

 

Type and standard

 

 

Product code	Degree of substitution	Viscosity/mPa(Water solution 2%,25°C)	Moisture/%	Chloride/%	pH value
MM6	0.5~0.7	80~200	≤10	≤3.5	5.5~7.5
MM8	0.7~0.9	200~800
MVH6	0.5~0.7	800~1200

Other qualification of medicine level:

Item	Target
Massfraction of Chloride(Cl)/%, ≤	3.5
Massfraction of As/%,≤	0.0002
Massfraction of Fe/%, ≤	0.004
Massfraction of heavy metal(Pb)/%, ≤	0.002

 

 

Application:

 

Acted as disintegrantt or excipient: the CMS of per-extraction lamella with 3%, semi-extraction lamella with 1.5%, it can shorten disintegration time, and improve the rigidity of tablet. It's effect of disintegrating will be good if adding 2% CMS when it be used in antibacterial and anti-inflammatory extract tablets. And at removing extraction lamella, it's effect of disintegrating will be good if the CMS’s dosage with lamella heavy 8% time(half intra-plus,and the other moiety plus at processing). The disintegrate effect of the CMS is 10 times of CMC.

Taking place of gelatin as the materials of capsule, tablet, and sugar coated place.

 

 

 

sodium starch glycolate(CMS)